The impact of obesity on upper airway anatomy as assessed by magnetic resonance imaging and obstructive sleep apnea endotypic traits.

ABSTRACT:

Introduction

Obesity is an important risk factor for obstructive sleep apnea (OSA) development. Likewise, obesity management is an important component of OSA treatment. We sought to evaluate the OSA endotypes as well as upper airway anatomy, using magnetic resonance imaging (MRI) in patients referred from a bariatric surgery clinic.

Methods

The SLIM-OSA trial (NCT04793334; IRB#191948) seeks to elucidate the mechanisms for why weight loss improves OSA in some but not all individuals. Participants underwent baseline research polysomnography. Six months following sleeve gastrectomy for those who underwent surgery, polysomnography was repeated. A subset of these individuals also completed upper airway magnetic resonance imaging (MRI). We evaluated relationships between upper air

SUBMITTER: Nokes B 

PROVIDER: S-EPMC12521235 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature