Multimodal prehabilitation is an effective strategy to reduce postoperative complications and improve physical function and anxiety in patients with colorectal cancer undergoing elective surgery: a systematic review and network meta-analysis.

ABSTRACT:

Background

Preoperative prehabilitation represents a viable approach to improve postoperative recovery and quality of life in colorectal cancer (CRC) patients, though debates persist regarding the efficacy of specific prehabilitation modalities.

Objective

This study aims to compare and rank prehabilitation strategies for enhancing postoperative outcomes in CRC patients through a network meta-analysis, identifying the optimal preoperative prehabilitation method.

Methods

We included randomized controlled trials (RCTs) assessing four prehabilitation strategies in CRC patients. Outcome measures focused on postoperative complications, hospital stay duration, 6-min walk test, and states of anxiety and depression. The effect sizes for dichotomous outcomes were measured by od

SUBMITTER: Li N 

PROVIDER: S-EPMC12521261 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature