Embolic efficacy and safety profile of UniPearls^® microspheres for hepatic artery embolization in domestic pigs.

ABSTRACT: UniPearls^® is a novel product of microspheres developed recently with unique features. This study aimed to investigate the embolic efficacy and safety of UniPearls^® for hepatic artery embolization (TAE) in vivo. Eighteen domestic pigs were randomly allocated to experimental group (n = 9) or control group (n = 9) and subjected to TAE procedure [set as day (D) 1]. UniPearls^® (size: 70 μm) was applied in experimental group, whereas HepaSphere^® (size: 30-60 μm) was applied in the control group. Domestic pigs were euthanized on D3, D8, and D29 (n = 3 per group at each timepoint). The mean injection speed, volume, and delivery performance score were 0.43 mL/min, 0.86 mL, and 3 points (highest score) in the experimental group, respectively; in compariso

SUBMITTER: Xi J 

PROVIDER: S-EPMC12521292 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature