Computerized chest radiograph analysis of air distribution after surfactant treatment of respiratory distress syndrome in extremely preterm infants.

ABSTRACT: The early air distribution after surfactant instillation can have implications for the development of lung injury in extremely preterm newborns with respiratory distress syndrome (RDS). The objective of this study is to determine lung air distribution and focal heterogeneity after surfactant treatment of RDS, using computerized image analysis of chest radiographs (CXRs). This is a retrospective observational non-paired study where CXRs were assessed within 6 h after surfactant instillation in the surfactant-treated group [STG] (n  =  52; median 24⁺⁴; range 22⁺⁰-27⁺⁵ weeks gestation) and at the same postnatal age in the pre-surfactant group [PSG] (n = 8; 25⁺³; 23⁺⁶-26⁺⁴). Digital image analysis was performed by ImageJ of lung

SUBMITTER: Fall J 

PROVIDER: S-EPMC12521333 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature