Multimodal ultrasound features for distinguishing classic and aggressive subtypes of papillary thyroid carcinoma.

ABSTRACT:

Background

To compare the sonographic features of papillary thyroid carcinoma (PTC) between classic and aggressive PTC subtypes to determine whether multimodal ultrasound (US) can aid in differentiating particular subtypes.

Methods

The retrospective cohort study included patients with histologically proven PTCs according to the World Health Organization classification of thyroid neoplasms between December 2022 and October 2024. Imaging findings were evaluated using the International Expert Consensus on US Lexicon for Thyroid Nodules. Associations between US features and intrinsic subtypes were assessed by the χ² or Fisher's exact test.

Results

Overall, 295 patients with 320 nodules (74 males with 81 nodules and 221 females with 239 nodules) were included. T

SUBMITTER: Deng B 

PROVIDER: S-EPMC12521462 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature