Genetic isolation drives divergent insecticide resistance between coastal and western Kenya Anopheles funestus populations.

ABSTRACT: Escalating levels of insecticide resistance and adaptive changes in mosquito populations threaten recent gains in malaria control. Understanding the molecular, ecological, and evolutionary processes driving these transformations is important for extending the effectiveness of current insecticides and informing the development of effective strategies and tools for vector control and insecticide resistance management. This study analyzed 103 whole-genome sequences from Anopheles funestus s.s. mosquitoes collected before the implementation of non-pyrethroid-based vector control tools in Kenya in 2017. Mosquito samples were collected from the western Kenya region (Bungoma, Migori and Kisumu Counties), the region with the highest malaria prevalence and the coastal region (Kilifi County), which

SUBMITTER: Polo B 

PROVIDER: S-EPMC12521475 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature