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Carbon dioxide elimination as a guide to venoarterial extracorporeal membrane oxygenation weaning: a prospective observational study.


ABSTRACT:

Background

Despite the increasing use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in cardiogenic shock (CS), reliable predictors of successful weaning remain poorly defined. This study investigated the role of carbon dioxide elimination parameters in VA-ECMO weaning.

Methods and results

To assess the potential role of end-tidal carbon dioxide (EtCO2) in predicting successful VA-ECMO weaning, we conducted a prospective observational study at Anzhen Hospital between January 2023 and December 2024. The primary endpoint was the predictive performance of EtCO2 and VCO2NL ratio for successful VA-ECMO weaning. Real-time EtCO2 monitoring was performed using infrared capnography in mechanically ventilated patients, and the

SUBMITTER: Yang Y 

PROVIDER: S-EPMC12521700 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature