Mapping the global intellectual landscape of inflammatory tumor microenvironment in colorectal cancer pathogenesis and prognostic research since this century.

ABSTRACT:

Background

Colorectal cancer (CRC) is one of the most prevalent gastrointestinal tumors worldwide. Complex interactions between tumor microenvironment (TME) and host inflammatory response influence CRC progression and recurrence. The current study provides a comprehensive bibliometric visualization of the current state and frontier trends of inflammatory TME in CRC.

Materials and methods

Scientific publications on the inflammatory TME in CRC from 2000 to 2024 were retrieved from the Web of Science Core Collection (WoSCC) database. Biblioshiny software was mainly applied for visualization and analysis of literature. CiteSpace software and VOSviewer software were used to validate the results.

Results

A total of 1593 articles related to CRC inflammatory TME have been ret

SUBMITTER: Mu H 

PROVIDER: S-EPMC12521722 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature