Intravenous thrombolysis versus endovascular thrombectomy in acute basilar artery occlusion-A multicenter cohort study.

ABSTRACT:

Background

Randomized controlled trials have demonstrated an improved outcome of basilar artery occlusion (BAO) with endovascular thrombectomy (EVT) compared to best medical treatment. However, a minority of the patients recruited up to 12-24 h from onset in the positive trials received intravenous thrombolysis (IVT), and a trial with a higher IVT rate did not show superiority of EVT. Thus, the efficacy and safety of EVT compared to IVT for BAO remain less clear.

Aims

We aimed to compare outcomes after IVT alone to EVT with or without IVT for acute BAO.

Methods

This international, observational, retrospective study included patients who received recanalization therapy for BAO at six centers between January 2010 and March 2024. The primary outcome was 3-month modified

SUBMITTER: Raty S 

PROVIDER: S-EPMC12521756 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature