A Three-Way Comparison of Nodular Lesions in H. pylori-Induced Gastritis, Non-Helicobacter pylori Helicobacter (NHPH)-Induced Gastritis, and NHPH-Induced MALT Lymphoma Reveals Their Distinct Endoscopic Predictors: Distribution for Bacterial Etiology and Morphology for Malignancy.

ABSTRACT:

Background

Nodular gastritis associated with Helicobacter pylori infection (HPi-NG) has long been recognized. Recently, similar mucosal changes have been reported with non-H. pylori Helicobacter (NHPH), including NHPH-induced gastric mucosa-associated lymphoid tissue lymphoma with a nodular gastritis-like appearance (NHPHi-MNG) and NHPH-induced nodular gastritis (NHPHi-NG). However, how bacterial species differences and the presence or absence of malignancy are reflected in endoscopic appearance has not been sufficiently investigated. This study aimed to clarify these relationships and to identify key endoscopic features that differentiate among the three clinically distinct entities.

Methods

We retrospectively analyzed 69 patients diagnosed at Hiroshima University Hospital

SUBMITTER: Kitadai Y 

PROVIDER: S-EPMC12521800 | biostudies-literature | 2025 Sep-Oct

REPOSITORIES: biostudies-literature