Zinc supplementation for postoperative sore throat prevention: evidence from a systematic review and meta-analysis.

ABSTRACT: Postoperative sore throat (POST) is a frequent complication of tracheal intubation that compromises patient comfort and satisfaction. This is due to airway irritation and inflammation. Zinc, which is known for its anti-inflammatory and wound-healing effects, has been investigated as a preventive treatment for POST. This protocol was registered in PROSPERO (CRD420250651708).Three databases, PubMed, The Cochrane Central Register of Controlled Trials, and Clinicaltrials.gov were searched using the keywords "Post operative sore throat," and "zinc." A literature search led to the retrieval of six clinical trials, of which three studies were included in the meta-analysis and all six studies were included in the systematic review. The data were synthesized using Cochrane Review Manager v.5.4.1. T

SUBMITTER: Bansal S 

PROVIDER: S-EPMC12521833 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature