Evaluating Clinically Directed Continuous Positive Airway Pressure to High Flow Nasal Cannula Transitions in Stable Preterm Infants Using Electrical Impedance Tomography: A Prospective, Observational Study.

ABSTRACT:

Objective

To assess lung aeration changes during clinically directed transitions from CPAP to HFNC in preterm infants using Electrical Impedance Tomography (EIT).

Design

Prospective, observational study.

Setting

Single-center, Level IV Neonatal Intensive Care Unit.

Patients

Infants born < 32 weeks gestational age (GA) undergoing a clinically indicated transition from CPAP to HFNC following ≥ 2 weeks of respiratory support.

Interventions

EIT data were recorded for 30-60 min before and after transition.

Main outcome measures

The primary outcome was change in end-expiratory lung impedance (ΔEELI). Infants were followed for 7 days following transition to assess for transition failure.

Results

From 15 subjects, 4257 total breaths were analyzed.

SUBMITTER: Rub DM 

PROVIDER: S-EPMC12522079 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature