Transmission components of hand, foot, and mouth disease in Guangdong Province and their association with meteorological factors: a modelling study.

ABSTRACT:

Background

Hand, foot, and mouth disease (HFMD) is a significant public health challenge, particularly in Guangdong Province, China. Although spatio-temporal dynamics of HFMD have been studied, inter-regional transmission patterns remain underexplored. This study investigates these patterns and the influence of meteorological factors to provide insights for more effective prevention strategies in the context of environmental factors.

Methods

We collected HFMD cases surveillance, population, and meteorological data from 21 cities in Guangdong from 2009 to 2017. Endemic-epidemic multivariate time-series model was used to analyze the case data, decomposing the HFMD risk into endemic, autoregressive, and spatio-temporal components, and investigating the influence of temperature

SUBMITTER: Tang H 

PROVIDER: S-EPMC12522236 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature