Cardiopulmonary bypass versus non-bypass surgery for tumor thrombus extending into the inferior vena cava or right atrium in non-cardiac malignancies: a systematic review and meta-analysis.

ABSTRACT:

Background

The role of cardiopulmonary bypass (CPB) in surgery for tumor thrombi extending into the inferior vena cava (IVC) or right atrium in noncardiac malignancies remains controversial. We systematically compared perioperative mortality and complications between the CPB and non-CPB approaches and summarized findings on surgical techniques and patient selection.

Methods

We searched major databases for studies (2015-2025) reporting surgical resection of IVC or right atrial tumor thrombi in noncardiac malignancies stratified by CPB use. Twenty studies were included in the qualitative synthesis, and nine were included in the quantitative meta-analysis. Pooled perioperative mortality and complications were compared via random effects models. Heterogeneity and correlations be

SUBMITTER: Al Mahrizi AD 

PROVIDER: S-EPMC12522322 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature