Eco-benign phytochemically-functionalized Ag-core Fe-shell bimetallic nanoparticles for targeted antioxidant and anti-inflammatory drug delivery.

ABSTRACT: The etiology of several degenerative diseases is linked to oxidative stress and inflammations. This study presents an eco-benign phytochemically-functionalized Ag-core Fe-shell (Ag@Fe) bimetallic nanoparticles (NPs) for targeted antioxidant and anti-inflammatory drug delivery. The NPs were synthesized, and modified with phytochemicals from the aqueous leaf extract of Costus lucanusianus; subsequently, characterized using advance microscopes and spectroscopes. Atomic force microscope revealed the grain size of 4.54 nm with the total projected area of 95.65% confirming the surface modification of the nanoparticles, and the energy dispersive spectroscope confirmed the strong presences of Ag and Fe. At 500 µg/mL, the NPs and ascorbic acid (standard) demonstrated similar (p < 0.05) antioxidant

SUBMITTER: Iheme CI 

PROVIDER: S-EPMC12522365 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature