Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis.

ABSTRACT:

Objective

To assess the efficacy and safety of various exercise modalities as therapeutic interventions for managing knee osteoarthritis.

Design

Systematic review with network meta-analysis.

Data sources

PubMed, Embase, Cochrane Library, Web of Science, CINAHL, PsycINFO, AMED, PEDro, Scopus, ClinicalTrials.gov, ICTRP, and ClinicalTrialsRegister.eu from database inception to August 2024.

Eligibility criteria for selecting studies

Randomised controlled trials comparing different exercise modalities, including aerobic exercise, flexibility exercise, mind-body exercise, neuromotor exercise, strengthening exercise, mixed exercise, and control group for patients with knee osteoarthritis.

Main outcome measures

Primary outcomes included pain, function, gait perf

SUBMITTER: Yan L 

PROVIDER: S-EPMC12522397 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature