Influence of healthy lifestyle on the incidence and survival of cancer and its comorbidities: evidence from a longitudinal cohort study.

ABSTRACT:

Objectives

To examine whether adherence to a healthy lifestyle affects cancer incidence, cancer-related comorbidities, and survival among cancer patients.

Methods

We analyzed 400,714 participants in the UK Biobank who were free of cancer and major noncommunicable diseases (NCDs)-including atherosclerotic cardiovascular disease (ASCVD), type 2 diabetes (T2D), chronic obstructive pulmonary disease (COPD), and chronic kidney disease (CKD)-at baseline and remained cancer-free for at least 180 days post-enrollment. A Healthy Lifestyle Index (HLI) was constructed based on six lifestyle factors and categorized into low, intermediate, and high levels. Multivariable Cox regression was used to estimate associations between HLI levels and the risks of cancer and cancer-related comorbid

SUBMITTER: Cheng X 

PROVIDER: S-EPMC12522411 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature