Impact of timing of computed tomography staging and patient factors on the detection of 'true' cN+ bladder cancer.

ABSTRACT:

Objectives

To evaluate whether computed tomography (CT) scans should be performed before or after transurethral resection of bladder tumour (TURBT) for accurate lymph node staging in clinically lymph node-positive bladder cancer (BCa). Additionally, to identify patient factors that can aid in predicting lymph node metastasis.

Patients and methods

In this retrospective, multicentre study, we analysed patients with cN+ M0 BCa staged by CT and treated with upfront radical cystectomy (RC) and pelvic lymph node dissection. We stratified patients by the interval between TURBT and CT into three groups: (1) before TURBT; (2) within 30 days after TURBT; and (3) more than 30 days post-TURBT. Staging accuracy, defined as concordance between clinical and pathological lymph node status,

SUBMITTER: von Deimling M 

PROVIDER: S-EPMC12522521 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature