Effect of goal-directed fluid therapy on the postoperative outcome in head and neck cancer surgery: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Postoperative complications have become the main cause of prolonged hospitalization and reduced postoperative survival rate among surgical patients. Goal-directed fluid therapy (GDFT) has been reported to reduce the incidence of postoperative complications and mortality, shorten the hospital stay, and improve the outcome in major abdominal surgery patients. However, the benefit of GDFT in patients undergoing head and neck cancer surgery remains controversial. The purpose of this study is to evaluate whether GDFT can reduce the occurrence of serious postoperative complications and shorten the postoperative hospital stay, compared with standard conventional fluid therapy in patients undergoing head and neck cancer surgery.

Methods

A total of 340 adult patients who s

SUBMITTER: Liang X 

PROVIDER: S-EPMC12522591 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature