The status of postapproval monitoring operation by the Institutional Animal Care and Use Committee in Korea.

ABSTRACT:

Background

Postapproval monitoring (PAM) is a critical component of Institutional Animal Care and Use Committee (IACUC) oversight, ensuring compliance with approved protocols and ethical animal research practices. While the PAM is not explicitly mandated under U.S. federal regulations, it has been widely recognized as an essential mechanism for verifying adherence to animal welfare standards. In contrast, Korea has formally integrated the PAM into its legal framework, making it a mandatory function of IACUCs.

Results

This study examines the implementation and perception of the PAM in Korean institutions through a survey of relevant professionals. These findings indicate that while awareness of the PAM is high, challenges such as limited manpower and institutional support hin

SUBMITTER: Lee J 

PROVIDER: S-EPMC12522620 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature