A systematic review and meta-analysis of Plasmodium infections and erythrocyte sedimentation rate in relation to disease severity.

ABSTRACT:

Background

Given the global burden of malaria and its impact on public health, there is a pressing need to understand the role of routine hematological parameters, particularly erythrocyte sedimentation rate (ESR), in malaria diagnosis and prognosis. This systematic review and meta-analysis aimed to comprehensively examine the differences in ESR between malaria patients and non-malarial controls, as well as between severe and non-severe malaria cases.

Methods

This systematic review and meta-analysis followed the PRISMA guidelines and was registered with PROSPERO (CRD42023482332). Comprehensive searches were conducted in ProQuest, Embase, Ovid, MEDLINE, PubMed, Scopus, and Google Scholar from inception to July 1, 2025, using terms related to "erythrocyte sedimentation rate" a

SUBMITTER: Kotepui M 

PROVIDER: S-EPMC12522621 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature