Associations of carotid flow velocity with cerebral perfusion and cerebral small vessel disease: a community-based prospective study.

ABSTRACT:

Objectives

To explore the associations of carotid artery hemodynamic parameters with cerebral perfusion and cerebral small vessel disease (CSVD) in a healthy population.

Methods

A total of 654 participants from the Kailuan community were included after those with incomplete data or carotid stenosis ≥ 50% were excluded. Carotid ultrasound was used to measure the peak carotid flow velocity (PSV), end-diastolic velocity (EDV), resistance index (RI), pulsatility index (PI) and carotid intima-media thickness (IMT) of the common carotid artery (CCA) and internal carotid artery (ICA). MRI was performed to assess cerebral perfusion and CSVD features, including white matter hyperintensities (WMH), lacunes (LA), cerebral microbleeds (CMB), and enlarged perivascular spaces (EPVS). Mult

SUBMITTER: Yang P 

PROVIDER: S-EPMC12522649 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature