Prepubertal testicular neuroendocrine tumor in postpubertal males: a case report and review of the literature.

ABSTRACT:

Background

In 2016, the World Health Organization classification system of testicular tumors included the new entity prepubertal-type testicular neuroendocrine tumor based on its morphological and molecular profile, and the realization that these tumors may occur in postpubertal men. For treatment and prognostic purposes, it is important to distinguish prepubertal-type testicular neuroendocrine tumor from the usual postpubertal-type testicular neuroendocrine tumor, because the former is benign unlike the latter. The distinction may be challenging. Therefore, we hope that ultrasound examination can play an important role in the differential diagnosis of testicular tumors.

Case presentations

These two cases involved postpubertal males, one is 41-years-old and the other is 62-y

SUBMITTER: Zhiqi Z 

PROVIDER: S-EPMC12522676 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature