Efficacy of herbal medicine Xiao-Feng-San combined with auricular acupuncture for atopic dermatitis: A randomized controlled trial.

ABSTRACT:

Background

Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a considerable burden. Xiao-Feng-San (XFS) has been widely used in traditional medicine for the wind-dampness-heat pattern. Auricular acupuncture (AA) may relieve AD symptoms, but its added benefit with XFS is unclear.

Methods

In this randomized, sham-controlled clinical trial, 156 adults with non-severe AD and wind-dampness-heat pattern, all of whom were prescribed XFS decoction, were additionally assigned to receive either AA (XFS plus AA group, n=78) or sham AA (XFS plus Sham AA group, n=78) for four weeks. The primary outcome was the change in the SCORAD index from baseline to week 4. Secondary outcomes included fexofenadine use, Dermatology Life Quality Index (DLQI), serum total IgE, an

SUBMITTER: Tran NT 

PROVIDER: S-EPMC12522700 | biostudies-literature | 2026 Jun

REPOSITORIES: biostudies-literature