Genomic diversity and surveillance of SARS-CoV-2 in Nigeria.

ABSTRACT:

Background

As Nigeria has the sixth-highest population in the world and a significant amount of inbound and outbound travel, the characterization of SARS-CoV-2 genomic diversity across the country is critical for understanding novel pandemic dynamics. We describe the genomic diversity of SARS-CoV-2 in Nigeria throughout the COVID-19 pandemic and examine the coverage of Nigeria's genomic surveillance system.

Methods

Genome sequences and sample metadata were downloaded from the GISAID repository. A beta regression was used to test for a relationship between fully resolved nucleotide proportion over time, as a proxy for data quality. Sample and sequencing source were compared to assess geographic coverage.

Results

A total of 7759 COVID-19 sequences collected from Februar

SUBMITTER: Kono TJY 

PROVIDER: S-EPMC12522711 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature