Preoperative C-reactive protein as a predictor of conversion and complications in laparoscopic cholecystectomy for acute cholecystitis.

ABSTRACT:

Introduction

Laparoscopic cholecystectomy (LC) is the gold standard for gallbladder surgery but may require conversion to open surgery in complicated cases. While preoperative C-reactive protein (CRP) is known to reflect inflammation, its predictive role in surgical outcomes remains debated. This study evaluated CRP as a predictor of surgical outcomes in acute cholecystitis and uncomplicated gallbladder stones, explicitly excluding choledocholithiasis to isolate gallbladder-specific inflammatory predictors.

Materials and methods

This retrospective cohort study analyzed 180 patients undergoing LC for acute cholecystitis (n = 76), chronic cholecystitis (n = 14), or uncomplicated cholelithiasis (n = 90). Preoperative CRP levels were measured, and ROC analysis determined optimal

SUBMITTER: Farahani PK 

PROVIDER: S-EPMC12522728 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature