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Prehospital extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest in goat with severe primary blast lung Injury-a pilot study.


ABSTRACT:

Background

Although extracorporeal cardiopulmonary resuscitation (ECPR) has shown promise for refractory out-of-hospital cardiac arrest (CA), limited data exist regarding its application in cases involving severe primary blast lung injury (PBLI). This study evaluated the feasibility, indications, complications, and early management of ECPR for refractory out-of-hospital CA in goats with severe PBLI.

Methods

Twenty adult goats (30.47 ± 4.74 kg) were randomly divided into five groups based on their distance from an 8 kg TNT-equivalent explosive: 2.5 m (n = 3), 3 m (n = 5), 4 m (n = 4), 5 m (n = 4), and 6 m (n = 4). Goats were positioned in concentric circles and fixed in special iron frames in the same direction (with the right chest facing the core of the explosion). Followin

SUBMITTER: Wu ZB 

PROVIDER: S-EPMC12522763 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature