Depression with risks for spontaneous abortion: a meta-analysis.

ABSTRACT:

Background

To assess the association between depression in women and the risk of spontaneous abortion (SA) after pregnancy.

Methods

Relevant studies were identified through searches of the PubMed, Web of Science, and Embase databases. The pooled effect sizes were presented as relative risk (RR) along with their respective 95% confidence intervals (95% CI), and data analysis was conducted using the random-effects model.

Results

A total of 31 studies involving 8,919,953 women were included in this meta-analysis. The results indicated a significant association between depression and increased risk of SA (RR = 1.34, 95% CI [1.27, 1.41], p < 0.001; I² = 87%). Sensitivity analysis did not identify outlier studies. Subgroup analysis enhanced the robustness and cre

SUBMITTER: Liu J 

PROVIDER: S-EPMC12522899 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature