The significant prognostic value of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in digestive system cancers: a systematic review and meta-analysis.

ABSTRACT:

Background

Digestive system cancers are a major global health burden, necessitating reliable and cost-effective prognostic biomarkers for clinical decision-making. The hemoglobin, albumin, lymphocyte, and platelet (HALP) score, an integrated immune-nutrition marker, has emerged as a potential prognostic tool in various malignancies. This meta-analysis evaluated the prognostic value of the HALP score in patients with digestive system cancers.

Methods

A systematic search was performed in PubMed, PMC, and Web of Science database for studies assessing HALP scores calculated from pre-treatment blood tests and reporting survival outcomes in patients with digestive system cancers. Hazard ratios (HRs) with 95% confidence intervals (CIs) were pooled to evaluate the prognostic signifi

SUBMITTER: Qian C 

PROVIDER: S-EPMC12523103 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature