Evaluation of an antibiotic stewardship program for promoting rational antibiotic use in an ICU in China.

ABSTRACT:

Background

The irrational use of broad-spectrum antibiotics in intensive care units (ICUs) has led to increasing bacterial resistance in recent years. However, research on the effectiveness of antimicrobial stewardship programs (ASPs) in Chinese ICUs is limited. This study aimed to assess the impact of ASP implementation on antibiotic use and bacterial resistance in a Chinese ICU.

Methods

 This retrospective, interventional study employed an interrupted time series design and was conducted in an ICU beginning on June 1, 2019. The ASP included the formation of a multidisciplinary team, the development of facility-specific criteria, prescriber education, the implementation of preauthorization processes, and retrospective prescription audit and feedback (RPAF). Patient data wer

SUBMITTER: Guo Y 

PROVIDER: S-EPMC12523123 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature