Determinants of mpox vaccination uptake among MSM during the 2022 outbreak: a single-centre retrospective study at Lyon University Hospital, France.

ABSTRACT:

Background

During the 2022 mpox outbreak, prophylactic vaccination was offered to at risk individuals, including men who have sex with men (MSM) with multiple sexual partners. We aimed to evaluate mpox vaccine first dose uptake in MSM and its determinants.

Methods

We conducted a single-centre, retrospective study using data from MSM presenting at the STI and HIV clinics of Lyon University Hospital between 1 January 2022 and 28 February 2023. First dose uptake of mpox vaccination (modified vaccinia Ankara-Bavarian Nordic) was evaluated across three groups of MSM: people living with HIV (PWH), HIV pre-exposure prophylaxis (PrEP) users and non-PrEP users (NPU). Uptake rates were compared with Chi2 analysis and multivariable hazard ratios (HR) were calculated using a Cox model.<

SUBMITTER: Merad Y 

PROVIDER: S-EPMC12523169 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature