Fluid removal intensity in intermittent hemodialysis for acute kidney injury: net ultrafiltration rate characterization and outcomes.

ABSTRACT: In patients receiving continuous renal replacement therapy (CRRT) for acute kidney injury (AKI), excessive net ultrafiltration (NUF) rates >1.75 mL/kg/h have been associated with increased mortality, delayed AKI recovery and complications of hemodynamic instability. There is limited information on fluid removal practices and NUF rates in AKI patients treated with intermittent hemodialysis (IHD).We conducted a retrospective study of AKI patients who underwent IHD at our center between 2020 and 2023. The primary outcome was NUF rate, assessed as body weight-scaled, body surfaces area-scaled and unadjusted values. Secondary outcomes included mortality and measures of renal recovery at 90 days (estimated glomerular filtration rate [eGFR], major adverse kidney events [MAKE], IHD dependence and

SUBMITTER: Paxton LK 

PROVIDER: S-EPMC12523464 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature