Multi-Omics Analysis Reveals Concentrate Supplementation Alleviates Body Weight Loss by Regulating Rumen Function in Lactating Tibetan Sheep During the Cold Season.

ABSTRACT: The parturition season of grazing Tibetan ewes spans from October to March, a period that exacerbates the adverse impacts of nutrient-deficient herbage on milk yield, body condition, and postpartum recovery. To alleviate the weight loss of ewes during the cold seasons, we provided concentrate supplements at four levels (dry matter (DM) basis), 260 g (C1), 440 g (C2), 520 g (C3), and 610 g (C4), alongside a basal diet of grazed pasture. A total of 96 multiparous Tibetan ewes (third parity, body weight: 45.17 ± 3.69 kg (body weight (BW) were enrolled within 12-18 h postpartum and randomly allocated to four dietary groups (n = 24 ewes per group). We measured growth performance, ruminal histomorphology, fermentation parameters, and digestive enzymes. A multi-omics technique (16S rRNA ge

SUBMITTER: Yang C 

PROVIDER: S-EPMC12523614 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature