Reduced vagal tone in women with adenomyosis.

ABSTRACT:

Abstract

Adenomyosis is an estrogen-dependent disease featuring chronic inflammation. This study was undertaken to investigate whether vagal tone is reduced in patients with adenomyosis compared with healthy women. We recruited 75 patients with adenomyosis, as diagnosed by a combination of ultrasound and gynecological examination, and 75 healthy women without adenomyosis, endometriosis, or other uterine disorders per ultrasound examination. All recruited subjects received an electrocardiogram evaluation, and their heart rate variability was assessed. In addition, lesional stiffness for patients with adenomyosis and myometrial stiffness for healthy controls were measured by ultrasound elastography. Severity of dysmenorrhea and the amount of menstrual blood loss were also evaluated.

SUBMITTER: Zeng W 

PROVIDER: S-EPMC12524039 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature