OPM-MEG in multiple sclerosis: Proof of principle, and the effect of naturalistic posture.

ABSTRACT: Multiple Sclerosis (MS) is a common neurological disorder in which myelin damage affects neuronal signalling. Magnetoencephalography (MEG - the measurement of magnetic fields generated by neuronal currents) offers metrics of brain function that relate directly to electrophysiological signalling, making it a valuable tool for exploring how abnormal function relates to MS symptoms. However, conventional MEG requires participants to be seated or supine with limited head and body motion. This makes it hard to measure brain function whilst simultaneously asking patients to carry out tasks they find challenging - many of which relate to movement. Here, we used a newly developed OPM-MEG system, with a wearable helmet and a lightweight backpack-mounted control unit, to measure MEG signals in peopl

SUBMITTER: Sanders BJ 

PROVIDER: S-EPMC12524172 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature