Predictors of Distant Metastasis in Patients with Medullary Thyroid Carcinoma.

ABSTRACT: Background/Objectives: The presence of distant metastases is the main cause of death in medullary thyroid carcinoma (MTC). However, due to the rarity of this cancer, few studies have thoroughly analyzed the variables influencing the development of distant metastases. The objective of this study was to evaluate, in patients with MTC, the factors associated with the occurrence of synchronous and metachronous distant metastases. Methods: An analytical, observational, retrospective cohort study was conducted at a tertiary hospital. Patients with histologically confirmed MTC, both sporadic and familial (MEN2 syndrome), were included. The influence of epidemiological variables, heredity, complementary tests, surgical factors, histological features, staging, and disease progression

SUBMITTER: Ros-Madrid I 

PROVIDER: S-EPMC12524247 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature