Archetypal Analysis Reveals Consistent Visual Field Patterns for Stimulus Size III and Size Modulation Perimetry in Glaucoma.

ABSTRACT:

Purpose

Optic nerve disorders produce identifiable visual field (VF) patterns. Size modulation perimetry (SMP) unlike standard automated perimetry (SAP) shows little degradation of retest variability with increasing VF damage. We hypothesize that VF testing with stimulus size III (size III) and SMP would reveal analogous patterns, supporting interchangeability in clinical practice.

Methods

We analyzed 274 same-day pairs of VFs from 83 eyes of patients with glaucoma. Participants underwent testing every 6 months using size III and SMP VFs. We converted raw sensitivity data to total deviation (TD) scores relative to normative datasets, censoring size III sensitivities below 20 decibels (dB). Archetypal analysis (AA) was applied separately to each modality to identify character

SUBMITTER: Szanto D 

PROVIDER: S-EPMC12524828 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature