Cognitive Impairment in Patients with Severe COPD: A Cross-Sectional Study.

ABSTRACT: Background/Objectives: Cognitive impairment (CI) in patients with chronic obstructive pulmonary disease (COPD) has been associated with reduced physical activity and decreased adherence to inhalation therapy. The primary aim of this study is to examine the prevalence of CI in patients with severe COPD and secondly compare outcomes with non-COPD comparators. Methods: Patients with severe COPD defined as forced expiratory volume in first second (FEV₁) <50% were recruited between January 2021 to January 2023 along with non-COPD comparators. CI was defined as a MoCA score < 26, adding one point for participants with ≤12 years of education. Additionally, two functional cognitive tests were included: the Continuous Reaction Time test (CRT) and a driving simulator. Res

SUBMITTER: Hansen KK 

PROVIDER: S-EPMC12525021 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature