A Closer Look at Potential Underlying Factors Related to Possible Disparity Between Sexes in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.

ABSTRACT: Background: Aneurysmal subarachnoid hemorrhage (SAH) is over twice as common in females compared to males, who may also experience more severe hemorrhages and worse outcomes. Differences in SAH severity, susceptibility to delayed cerebral ischemia (DCI), and treatment responsiveness may underlie this disparity. This study evaluated sex-based differences in DCI timing, severity, treatment responsiveness, and outcomes after SAH. Methods: We analyzed 650 consecutive SAH patients admitted to RWTH Aachen University Hospital (2006-2021). SAH severity was assessed via the (World Federation of Neurological Surgeons) WFNS and modified Fisher scales. DCI-related infarction was defined as new infarcts on CT not present initially or within 48 h post-aneurysm occlusion. Endovascular rescu

SUBMITTER: Veldeman M 

PROVIDER: S-EPMC12525044 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature