Prenatal sugar exposure shapes late-life human capital and health.

ABSTRACT: Maternal sugar consumption during pregnancy may have a variety of effects on offspring. We exploit the abolishment of the rationing of sweet confectionery in the United Kingdom on 1949 April 24, and its subsequent reintroduction some months later, in an era of otherwise uninterrupted rationing of confectionery (1942-1953), sugar (1940-1953), and many other foods, and we consider effects on late-life cardiovascular disease, body mass index (BMI), height, type-2 diabetes, and the intake of sugar, fat, and carbohydrates, as well as cognitive outcomes and birth weight. We use individual-level data from the UK Biobank for cohorts born between April 1947 and May 1952. We also explore whether one's genetic "predisposition" to the outcome can moderate the effects of prenatal sugar exposure. We fin

SUBMITTER: van den Berg GJ 

PROVIDER: S-EPMC12525142 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature