N-Terminal Metal-Binding Domain of Arabidopsis IBR5 Is Important for Its in Planta Functions.

ABSTRACT: Indole-3-acetic acid (IAA), the predominant natural auxin, is a plant hormone that regulates growth and development in response to various internal and external signals. Arabidopsis thaliana (Arabidopsis) indole-3-butyric acid response 5 (AtIBR5, AT2G04550) encodes a dual-specificity phosphatase in Arabidopsis. The atibr5 mutant exhibits reduced sensitivity to indole-3-butyric acid (IBA), a precursor of IAA, but is also less responsive to another plant hormone, abscisic acid (ABA). We report that AtIBR5 contains a rubredoxin-like domain in its N-terminal region, in addition to the previously identified dual-specificity phosphatase domain. The rubredoxin-like domain of AtIBR5, when expressed in Escherichia coli, binds zinc through four cysteine residues in

SUBMITTER: Yeon J 

PROVIDER: S-EPMC12525521 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature