¹H NMR Relaxation Processes in Lung Tissues at Low Magnetic Fields.

ABSTRACT: Proton spin-lattice and spin-spin NMR relaxation studies were conducted on lung tissue samples from 10 patients. For each case, relaxation properties of tumor tissue were compared with those of the corresponding reference tissue. The spin-lattice relaxation measurements were performed over a wide frequency range, from 10 kHz to 10 MHz, spanning three orders of magnitude. These were complemented by both spin-lattice and spin-spin relaxation data acquired at 18.7 MHz. Notably, the spin-spin relaxation process exhibited a bi-exponential character. This relaxation behavior was quantitatively analyzed using dedicated models to achieve two main goals: to evaluate the diagnostic potential of low-field NMR relaxometry, and to gain insights into the dynamics of water and macromolecules in tissue, i

SUBMITTER: Kolodziejski K 

PROVIDER: S-EPMC12525575 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature