Green Synthesis and Characterization of <i>Rosa roxburghii</i> Tratt.-Mediated Gold Nanoparticles for Visual Colorimetric Assay of Tiopronin.

ABSTRACT: This study used Rosa roxburghii Tratt. crude extract (RR) as a reducing, stabilizing, and modifying agent for the green synthesis of gold nanoparticles (RR-AuNPs) via the one-pot method for the first time and established a novel colorimetric sensor for detecting tiopronin. Initially, RR-AuNPs with a uniform particle size and stable dispersion were prepared using the reducing property of RR. Upon the introduction of tiopronin, the drug binds to the surface of RR-AuNPs through Au-S bonds and hydrogen bonds, inducing a significant aggregation of RR-AuNPs. The absorbance of the RR-AuNP solution exhibited a linear relationship with the tiopronin concentration in the range of 0.17 μM to 16.67 μM (y = 1.9157 - 0.0972x), with a detection limit of 0.19 μM. The colorimetric sensor was success

SUBMITTER: Liu D 

PROVIDER: S-EPMC12525941 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature