Anti-Obesity Potential of Modified Pomelo-Peel Dietary Fiber-Based Pickering Emulsion.

ABSTRACT:

Objectives

In response to the high prevalence of global obesity and associated metabolic diseases, this study aimed to investigate the effects of Pickering emulsions stabilized by cellulase-hydrolyzed pomelo peel insoluble dietary fiber (IDF), namely EPI and its octenyl succinic anhydride (OSA)-modified form (OSA-EPI), on alleviating high-fat diet (HFD)-induced metabolic disorders in mice.

Methods

Male C57BL/6J mice were subjected to an HFD-induced obesity model. Biochemical index determination, histopathological examination, gut microbiota analysis, and short-chain fatty acids (SCFAs) analysis were used to study the potential efficacy of pomelo peel IDF-based emulsion (EPI and OSA-EPI) in alleviating obesity and related metabolic diseases.

Results

The findings demons

SUBMITTER: Peng K 

PROVIDER: S-EPMC12526110 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature