Coupled Impact of Anthocyanin and Mineral Concentrations in Cranberry Juice on Gut Microbiota and Function Modulation: A First Demonstration.

ABSTRACT: Cranberry juice (CJ), a natural source of anthocyanins, may provide additional health benefits when enriched, as anthocyanins have been shown to influence gut microbiota composition. This study investigated the effects of varying anthocyanin and mineral concentrations in CJ on gut microbiota in mice. Using electrodialysis with filtration membranes (EDFM), five CJ samples with different anthocyanin/mineral enrichment levels (0/0, -31/-85%, -19/-70%, 26/-32%, and 44/-60%) were produced and administered to C57BL/6J mice for four weeks. Gut microbiota composition was analyzed via 16S rRNA sequencing, and inflammation was determined in macroscopic observations of intestinal tissues. While α and β diversity remained unchanged, differential abundance analysis revealed that gut microbiota changes

SUBMITTER: Revellat E 

PROVIDER: S-EPMC12526315 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature