PH-Sensitive Release of Functionalized Chiral Carbon Dots from PLGA Coatings on Titanium Alloys for Biomedical Applications.

ABSTRACT: Titanium and its alloys are the most widely used metallic materials for bone contact implants. However, despite advances in implant technology, these alloys are still susceptible to post-operative clinical complications such as inflammation, which is often joined by infections and biofilm formation. A number of coatings were studied to overcome the drawbacks of these complications, but the controlled release of bioactive molecules over the first few days and the adhesion of the coating to the substrate remain recognized challenges. Carbon dots and the antibacterial potential of chiral carbon dots (CCDs) were recently reported, and their chirality was identified as a major contribution to the bactericidal effect. This study aimed to achieve a stimuli-responsive medium-term controlled releas

SUBMITTER: Lopez-Munoz R 

PROVIDER: S-EPMC12526717 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature