Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade.

ABSTRACT:

Purpose

Sepsis and septic shock in patients with neutropenia are associated with high mortality. We investigated the features and outcome predictors of neutropenic sepsis in the last decade.

Methods

Consecutive patients who were admitted to the intensive care unit (ICU) of a French university-affiliated hospital in 2012-2022, met criteria for sepsis or septic shock, and had neutropenia were included retrospectively. Patient features were collected and compared for 2012-2017 and 2018-2022. Factors associated with hospital mortality were sought by univariate and multivariate analyses.

Results

Of the 185 patients, 85 were admitted in 2012-2017 and 100 in 2018-2022. The more recent group was older and had a heavier comorbidity burden but had a hospital mortality rate of 4

SUBMITTER: Guillotin F 

PROVIDER: S-EPMC12527136 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature