Generation and assessment of high-quality fat-tailed dunnart oocytes following superovulation in prepubertal animals†.

ABSTRACT: The fat-tailed dunnart, Sminthopsis crassicaudata, is a mouse-sized, polyovular, solitary dasyurid marsupial found in central and southern Australia. With the establishment of a chromosome-scale genome assembly, induced pluripotent stem cells, and targeted genetic editing, the dunnart is emerging as the laboratory marsupial model for comparative development, reproductive, and conservation biology. The development of assisted reproductive technologies are critical to achieving these goals in this species. Assisted reproductive technology requires a large number of mature oocytes, which are typically collected through stimulated and synchronized female reproductive cycles. While protocols for induced ovulation or superovulation are standard in many placental mammals, there are no methods to

SUBMITTER: Liu J 

PROVIDER: S-EPMC12527288 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature