Measles seroprevalence by birth cohort across the lifespan: a population-based, cross-sectional serosurvey in British Columbia, Canada.

ABSTRACT:

Background

In 2025, the province of British Columbia (BC), Canada, experienced heightened measles activity, mostly involving unvaccinated communities. Publicly funded measles vaccination for children aged 12 months has been routine since 1969, with a second dose at age 18 months added in 1996, and rescheduled to 4 to 6 years (school entry) in 2012. We aimed to assess population-based measles seroprevalence in relation to historic measles endemicity and vaccination considerations.

Methods

In August 2024, we undertook a cross-sectional serosurvey, testing more than 1000 anonymized residual sera for measles antibody. We collected sera from outpatients attending a laboratory network in the Lower Mainland, BC, with equal numbers from 10 age groups, from 1 year to older than 80 ye

SUBMITTER: Kaweski SE 

PROVIDER: S-EPMC12527300 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature