Moving From CT-First to MRI-First Paradigm in Acute Ischemic Stroke: Treatment Rates, Time Metrics, Safety, and Outcomes.

ABSTRACT:

Background and purpose

Neuroimaging is essential before intravenous thrombolysis (IVT) and endovascular treatment (EVT) for acute ischemic stroke (AIS). In May 2018, our center transitioned from computed tomography (CT) to magnetic resonance imaging (MRI) as the first-line imaging for suspected AIS. We aimed to assess the consequences of an MRI-based paradigm on patients' selection, rates of acute treatment, time metrics, safety of both IVT and EVT, and clinical outcomes.

Methods

Using data from the Acute STroke Registry and Analysis of Lausanne (ASTRAL), we analyzed an equal number of patients from the CT-period (December 2012 to May 2018) and the subsequent MRI-period (May 2018 to August 2022). We performed univariable and multivariable analysis.

Results

We included

SUBMITTER: Rapillo CM 

PROVIDER: S-EPMC12527576 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature